Why Only a "Handful of Companies" Reaped Enormous Profits from mRNA Vaccines —— How Patent Strategy Decided Pharmaceutical Supremacy [Paid]
June 16, 2026 · Shishido & Associates
The mRNA vaccines that saved the world during the COVID-19 pandemic. Yet the enormous profits went to only a handful of companies, such as Moderna, Pfizer, and BioNTech. Despite being a revolutionary medical technology, why did an "oligopoly of a few companies" emerge?
The answer lies less in the technology itself than in "dominant design" and patent strategy. In this article, we unravel the following mysteries from an IP perspective.
- Why mRNA became the dominant design (the de facto standard) for preventive vaccines
- The "international divisional and continuation application" mechanism built into the foundational patent
- Why a small German startup, BioNTech, was able to compete on equal terms with major pharmaceutical companies
- Why the basic researchers Drs. Karikó and Weissman won the Nobel Prize
- And what is being contested between companies right now (the Moderna vs Pfizer/BioNTech patent litigation)
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